The best Side of cees dekker
The best Side of cees dekker
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‘Yes, that's about suitable. I hunt for a Actual physical idea of Organic methods within a base-up way. I believe you can distinguish 3 lines of analysis in my team in the mean time. The main issues chromosome framework: How does one obtain a metre-prolonged DNA polymer folded and organised in this kind of microscopic cell? We've got formulated visualisation methods that let us to check how, for instance, SMC proteins loop DNA (video clip on Youtube) as a way to Construct up chromosomes.
It absolutely was only during the nineties though, when nanotechnology had Sophisticated to some amount exactly where one molecules may be manipulated, that the first experimental units commenced to appear.
Dynamics of initiation, termination and reinitiation of DNA translocation through the motor protein EcoR124I
Our get the job done was rapidly followed up by Other individuals, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 revealed their results on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.
This yielded a breakthrough. In only a few months, we were ready to measure transportation by way of an individual solitary-walled carbon nanotube. According to small-temperature experiments by an excellent PhD student in my team, Sander Tans (now a valued colleague and professor at Delft College of Technologies with an Energetic analysis lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up authentic quantum wires with quite lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Microbiology has only been around for any century, considering the fact that we began to study micro-organisms much more significantly. I believed nanobiology was an ideal time period, for the reason that all molecular biological related interactions take place in the nanoscale: a protein is several nanometres in measurement, DNA is 2 nm thick.’
All parameters have been the exact same for every panel in this video, apart from the Original placement with the ceesdekker.net 6hb rod (proven in blue) on the nanopore. Simulations that terminated early due to translocation with the rod through the pore are marked by a grey qualifications.
Finding out DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
Imagine if, as an alternative to utilizing common prime-down silicon electronics, transistors might be crafted from the bottom up applying solitary natural and organic molecules since the switching components? This concept, which became The idea of today’s subject of molecular electronics, initial emerged from the seventies.
But carbon nanotubes have remained a study topic of considerable interest to many. Indeed, the outlook on using carbon nanotubes to build practical devices, in spots which include radio-frequency electronics, electronic electronics and versatile electronics, remains vibrant.
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Cees Dekker is Distinguished University Professor at TU Delft. Trained as being a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His present study focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, especially SMC motor protein; and (iii) developing a residing artificial cell from lifeless molecules. Dekker is surely an elected member in the KNAW and fellow for the APS as well as the IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)